Adit 0.025% Cream 20gm

INTRODUCTION

ADIT 0.025% contains Tretinoin which belongs to the group of medicines called retinoids. It is used for the topical treatment of acne and photo-aging. Acne vulgaris is a common skin condition that occurs in teens, when hair follicles of the skin plug with oil and dead skin cells. Symptoms includes inflammation, large, reddish pus-filled pimples and formation of comedones. Photo-aging refers to premature skin aging caused by repeated or prolonged exposure to sun or other light sources resulting in development of wrinkles, pigmentation, whiteheads, blackheads and sagging of loose skin.

Tretinoin reduces pimples by making the surface of the skin thinner and pores, so that they become less likely to be blocked and inflamed. It stimulates the growth of new skin cells more rapidly which results in reduction of fine lines, wrinkles and dark spots. Wash the affected area thoroughly before applying this medicine. Do not apply too much of this medicine, as it may result in skin irritation. Along with the treatment, avoid exposure to sunlight as much as possible. Do not use this medicine if you have sunburn or other skin conditions.

The most common side effects of using this medicine are feeling of warmth, stinging, excessive redness, or worsening of acne. These are usually normal and temporary. You will begin to notice improvement in your skin after 2-3 weeks of starting tretinoin, but it may take 6-12 weeks for more definite benefits. So, continue to use this medicine, as long as your doctor tells you to do so, to obtain better results. Before using this medicine consult your doctor if you are pregnant or breastfeeding.

USES OF ADIT 0.025%

• Treats acne vulgaris and photo-aging

HOW ADIT 0.025% WORKS

Tretinoin is a potent comedolytic which promotes lysis of keratinocytes, prevents horny cells from binding to each other and stimulates epidermal cell turnover. It reduces pimples by making the skin surface thinner and pores, so that they become less likely to be blocked and inflamed. It stimulates the growth of new skin cells more rapidly which results in reduction of fine lines, wrinkles and dark spots.

DIRECTIONS FOR USE

Apply this medicine once or twice daily on the affected skin area, usually before going to bed or as directed by your physician. It is for external use only. Before application, wash the affected area with a mild, non-medicated soap. Pat the skin dry. Take the required amount of the medicine and apply on the entire affected area lightly.

Your doctor will decide the correct dose and duration for you depending upon your condition. Do not apply too much of this medicine, as it may irritate your skin. Avoid contact of this medicine with eyes, ears, nose and other mucous membranes. If contact happens, wash it thoroughly with water. Do not apply this medicine on wounded, damaged or cut skin. Continue to apply this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF ADIT 0.025%

Skin irritation:

Avoid hot showers because hot water can irritate the skin. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If it does not get better, speak to your doctor.

Talk to your doctor, if you are taking,

• Certain medicines which are known to make your skin sensitive to sunlight (e.g. some diuretics (furosemide) or antibiotics)
• Medicines used for certain psychiatric conditions
• Other skin medications containing sulfur, resorcinol, benzoyl peroxide or salicylic acid
• Cosmetics containing alcohol, lime and spices (e.g. after-shave lotions, soaps, shampoos or perfumes)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ADIT 0.025%

How long will it take for ADIT 0.025% to show results?

You will begin to notice improvement in your skin after 2-3 weeks of starting tretinoin, but it may take 6-12 weeks for more definite benefits. So, continue to use this medicine, as long as your doctor tells you to do so, to obtain better results

Can ADIT 0.025% cause acne?

Yes. Initially, treatment with this medicine may cause worsening of acne, but it is normal and usually temporary and disappear as the treatment continues. Meanwhile, avoid hot showers because hot water can irritate the skin. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If it does not get better, speak to your doctor.

Can ADIT 0.025% remove scars?

Yes. This medicine induces peeling of existing skin and stimulates the growth of new skin cells more rapidly which results in reduction of dark spots, scars, fine lines and wrinkles.

Can we undergo cosmetic treatments while taking ADIT 0.025%?

Please consult your doctor, before undergoing any cosmetic treatment, so that your doctor will decide whether you can continue taking this medicine or not. However, it is advised to not undergo any skin care treatment containing alcohol, lime and spices or other irritants while using this medicine.

REFERENCES

1. KD. Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 894.

2. Craig Burkhart, Dean Morrell and Lowell Goldsmith. Dermatological Pharmacology. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1810.

3. Gerald G. Briggs and Roger K. Freeman. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 3898-3899.

4. Taro Pharmaceuticals USA. To Evaluate the Therapeutic Equivalence and Safety of TRETINOIN CREAM, 0.05% and RLD in the Treatment of Acne Vulgaris. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on May 2018] [Accessed 2nd December 2020]

5. Siddharth Mukherjee, Abhijit Date, Vandana Patravale, Hans Christian Korting, Alexander Roeder  and Günther Weindl. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. NCBI; PMC US National Library of Medicine, National Institute of Health. December 2006. [Accessed 2nd December 2020]

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